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Microcontact Printing

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Biological Microarrays

Part of the book series: Methods in Molecular Biology ((MIMB,volume 671))

Abstract

Microcontact printing (μCP) is a useful technique for transferring certain molecules onto surfaces with high spatial resolution using elastomeric stamps. The stamp for μCP is fabricated by replica molding from a master made by microlithography. After wetting with a type of material as an “ink,” the stamp comes into contact with the substrate. The ink is selectively transferred onto parts of the substrate wherever the stamp makes direct contact, to generate patterns and structures with designated features. Self-assembled monolayers (SAMs) and μCP are useful in many different fields, e.g., in the studies of protein adsorption, cell attachment, and in the construction of sensors.

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Acknowledgments

We thank Ms. Wenwen Liu, Mr. Bo Yuan, Mr. Kang Sun, and Mr. Dingbin Liu for the technical assistance. We thank the Chinese Academy of Sciences, the NSFC, MOST, and the Human Frontier Science Program for the financial support.

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Authors and Affiliations

  1. National Center for NanoScience & Technology, Beijing, China

    Yunyan Xie & Xingyu Jiang

Authors
  1. Yunyan Xie
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  2. Xingyu Jiang
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Corresponding author

Correspondence to Xingyu Jiang .

Editor information

Editors and Affiliations

  1. , MIT Division of Health Sciences and Tech, Harvard Medical School, Landsdowne St. 65, Cambridge, 02139, Massachusetts, USA

    Ali Khademhosseini

  2. , Department of Mechanical and Aerospace E, Seoul National University, Kwanak-gu, Shinlim-dong 56-1-1, Seoul, 151-742, Korea, Republic of (South Korea)

    Kahp-Yang Suh

  3. Biophage Pharma, Inc., Royalmount Ave. 6100, Montreal, H4P 2R2, Québec, Canada

    Mohammed Zourob

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© 2011 Springer Science+Business Media, LLC

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Xie, Y., Jiang, X. (2011). Microcontact Printing. In: Khademhosseini, A., Suh, KY., Zourob, M. (eds) Biological Microarrays. Methods in Molecular Biology, vol 671. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59745-551-0_14

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  • DOI: https://doi.org/10.1007/978-1-59745-551-0_14

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-934115-95-4

  • Online ISBN: 978-1-59745-551-0

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