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In Vivo Patch-Clamp Technique

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Patch-Clamp Analysis

Part of the book series: Neuromethods ((NM,volume 38))

Abstract

The whole-cell patch-clamp recording technique (Marty and Neher, 1995) is nowadays a standard method for studying electrophysiological properties of the cellular membranes and synaptic inputs. This technique has been applied mainly to in vitro preparations such as culture cells, dissociated cells, and brain slices, contributing greatly to our understanding of ionic mechanisms of channels/receptors, and synaptic transmission in the neuronal circuits. However, the physiological significance of the neuronal and synaptic activities observed in such in vitro preparations remains to be clarified.

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Authors and Affiliations

  1. Department of Integrative Physiology, Kyushu University, Fukuoka, Japan

    Hidemasa Furue, Toshihiko Katafuchi & Megumu Yoshimura

Authors
  1. Hidemasa Furue
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  2. Toshihiko Katafuchi
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  3. Megumu Yoshimura
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Editor information

Editors and Affiliations

  1. Department of Physiology, University of Saskatchewan, Saskatoon, Canada

    Wolfgang Walz

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© 2007 Humana Press Inc., Totowa, NJ

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Furue, H., Katafuchi, T., Yoshimura, M. (2007). In Vivo Patch-Clamp Technique. In: Walz, W. (eds) Patch-Clamp Analysis. Neuromethods, vol 38. Humana Press. https://doi.org/10.1007/978-1-59745-492-6_7

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  • DOI: https://doi.org/10.1007/978-1-59745-492-6_7

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-705-1

  • Online ISBN: 978-1-59745-492-6

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