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Magnetic Nanoparticles for Local Drug Delivery Using Magnetic Implants

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Book cover Micro and Nano Technologies in Bioanalysis

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 544))

Summary

This chapter is a brief description of the state of the art of the field of targeted drug delivery using magnetic implants. It describes the advantages and drawbacks of the use of internal magnets to concentrate magnetic nanoparticles near tumor locations, and the different approaches to this task performed in vitro and in vivo reviewed in literature are presented.

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Acknowledgments

Financial support by the Spanish Ministry of Science (through projects NAN2004-09270-CO3-03, and CONSOLIDER NANOBIOMED) and the Department of Science, Technology and University of the Government of Aragón is acknowledged. We also acknowledge Alba García and Dr. José A. García de Jalón from the Animal Pathology Department at the University of Zaragoza for histopathology images. Dr. Clara Marquina, Dr. Manuel Arruebo, Dr. Valeria Grazu, Dr. Jesús M. de La Fuente, Dr. Gerardo Goya, Dr. Américo Viloria, Dr. Teresa Higuera, Javier Gómez-Arrúe, Alicia Laborda, Ángel García, María Moros, Laura Asín, Teobaldo Torres, and Sara Puertas also played key parts in this research.

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Authors and Affiliations

  1. Instituto Universitario de Investigación en Nanociencia de Aragón (INA), Instituto de Ciencia de Materiales de Aragón (ICMA), Universidad de Zaragoza-CSIC, Edif. Inter. II, 50009, Zaragoza, Spain

    Rodrigo Fernández-Pacheco, J. Gabriel Valdivia & M. Ricardo Ibarra

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  1. Rodrigo Fernández-Pacheco
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  2. J. Gabriel Valdivia
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  3. M. Ricardo Ibarra
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    © 2009 Humana Press, a part of Springer Science+Business Media, LLC

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    Fernández-Pacheco, R., Valdivia, J.G., Ibarra, M.R. (2009). Magnetic Nanoparticles for Local Drug Delivery Using Magnetic Implants. In: Foote, R., Lee, J. (eds) Micro and Nano Technologies in Bioanalysis. Methods in Molecular Biology™, vol 544. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59745-483-4_35

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    • DOI: https://doi.org/10.1007/978-1-59745-483-4_35

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    • Publisher Name: Humana Press, Totowa, NJ

    • Print ISBN: 978-1-934115-40-4

    • Online ISBN: 978-1-59745-483-4

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