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Methods of Evaluating the Effect of Pharmacological Drugs On Aging and Life Span in Mice

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Biological Aging

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 371))

Abstract

The methodology of testing anti-aging drugs in laboratory mice is presented. It includes the selection of mouse strain, sex, age at start of treatment, housing conditions, design of the long-term study, some noninvasive methods of assessment, pathology examination, and statistical treatment of the results.

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Authors and Affiliations

  1. Department of Carcinogenesis and Oncogerontology, N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia

    Vladimir N. Anisimov, Irina G. Popovich & Mark A. Zabezhinski

Authors
  1. Vladimir N. Anisimov
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  2. Irina G. Popovich
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  3. Mark A. Zabezhinski
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Editor information

Editors and Affiliations

  1. Department of Biology, University of Alabama at Birmingham, Birmingham, AL

    Trygve O. Tollefsbol

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© 2007 Humana Press Inc., Totowa, NJ

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Anisimov, V.N., Popovich, I.G., Zabezhinski, M.A. (2007). Methods of Evaluating the Effect of Pharmacological Drugs On Aging and Life Span in Mice. In: Tollefsbol, T.O. (eds) Biological Aging. Methods in Molecular Biology™, vol 371. Humana Press. https://doi.org/10.1007/978-1-59745-361-5_17

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  • DOI: https://doi.org/10.1007/978-1-59745-361-5_17

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-658-0

  • Online ISBN: 978-1-59745-361-5

  • eBook Packages: Springer Protocols

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