Abstract
As transposomics is extended to genome scale, appropriate statistical methods need to be developed to assign significance to gene essentiality. In this chapter, the author presents a set of steps that, together with genome-scale insertion data and the complete genome sequence of a prokaryote, can be used to classify the genes of the organism as either “essential” or “nonessential.”
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© 2008 Humana Press Inc., a part of Springer Science+Business Media, LLC
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Balázsi, G. (2008). Statistical Evaluation of Genetic Footprinting Data. In: Osterman, A.L., Gerdes, S.Y. (eds) Microbial Gene Essentiality: Protocols and Bioinformatics. Methods in Molecular Biology™, vol 416. Humana Press. https://doi.org/10.1007/978-1-59745-321-9_23
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DOI: https://doi.org/10.1007/978-1-59745-321-9_23
Publisher Name: Humana Press
Print ISBN: 978-1-58829-378-7
Online ISBN: 978-1-59745-321-9
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