Abstract
The study of protein-protein and protein-DNA interactions is critical to understand biological processes. This article presents the methodology to create peptide microarrays in situ for the high-throughput screening of complex biomolecules. The in situ ink-jet peptide synthesis results in a conservation of costly reagent and amino acids, whereas providing a means to produce denser peptide arrays. A smaller amount of test sample is required to observe interaction when using these high-density peptide arrays.
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© 2007 Humana Press Inc., Totowa, NJ
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Antohe, B.V., Cooley, P.W. (2007). In Situ Synthesis of Peptide Microarrays Using Ink-Jet Microdispensing. In: Rampal, J.B. (eds) Microarrays. Methods in Molecular Biology™, vol 381. Humana Press. https://doi.org/10.1007/978-1-59745-303-5_15
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DOI: https://doi.org/10.1007/978-1-59745-303-5_15
Publisher Name: Humana Press
Print ISBN: 978-1-58829-589-7
Online ISBN: 978-1-59745-303-5
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