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Chemistry for Chemical Genomics

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Chemical Genomics

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 310))

Abstract

New methods and strategies have been developed to design and use small molecules that allow the functional dissection of molecular pathways, cells, and organisms by selective small-molecule ligands or modulators. In this overview, we are focusing on diversity aspects, design methods, and chemical synthesis strategies for the application of small molecules as tools for chemical genomics. Examples for different successful chemical-genomics strategies include the selection of diverse drug-like molecules, target family—focused compound libraries, natural-product chemistry, and diversity-oriented synthesis.

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Author information

Authors and Affiliations

  1. NexusPharma, Langhorne, PA

    Lutz Weber (President)

Authors
  1. Lutz Weber
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Editors and Affiliations

  1. CamBP Ltd., Cambridge, UK

    Edward D. Zanders PhD

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© 2005 Humana Press Inc.

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Weber, L. (2005). Chemistry for Chemical Genomics. In: Zanders, E.D. (eds) Chemical Genomics. Methods in Molecular Biology™, vol 310. Humana Press. https://doi.org/10.1007/978-1-59259-948-6_2

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  • DOI: https://doi.org/10.1007/978-1-59259-948-6_2

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-399-2

  • Online ISBN: 978-1-59259-948-6

  • eBook Packages: Springer Protocols

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