Abstract
Glycosylation is a major posttranslational modification that produces heterogeneity in a protein and results in a group of structurally different species called glycoforms. Protein-associated oligosaccharides are large, structurally diverse molecules, and the biological roles ascribed to them are numerous. Some of these functions include the following: intercellular adhesion, adhesion of microorganisms, including viruses to target cells, and modulation of immunological activity of polypeptide chains.
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O’Shannessy, D J., Voorstad, P. J., and Quarles, R. H. (1987) Quantitation of glycoproteins on electroblots using the biotin-streptavidin complex. Anal Biochem. 163, 204–209.
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© 1998 Humana Press Inc., Totowa, NJ
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Szewczyk, B., Summers, D.F. (1998). Purification of Glycoproteins and Their Use as Immunogens. In: Pound, J.D. (eds) Immunochemical Protocols. Methods in Molecular Biology™, vol 80. Humana Press. https://doi.org/10.1007/978-1-59259-257-9_9
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DOI: https://doi.org/10.1007/978-1-59259-257-9_9
Publisher Name: Humana Press
Print ISBN: 978-0-89603-493-8
Online ISBN: 978-1-59259-257-9
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