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Blood Biomarkers for Stroke Differentiation

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Stroke Biomarkers

Part of the book series: Neuromethods ((NM,volume 147))

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Abstract

Acute stroke is a neurological emergency. Time sensitive treatment decisions depend on the correct diagnosis of stroke and its subtype: ischemic or hemorrhagic. An early diagnosis of ischemic stroke is required for prompt decision making and administration of thrombolytic therapy within the time frame. Non-contrast computed tomography (CT) scan is currently used for the diagnosis of stroke. However, CT scan facility is not widely available in resource limited settings. Therefore, there is an urgent need to identify blood-based biomarkers for rapid diagnosis and differentiation of stroke in the acute stages for better treatment and management strategies. A blood test that can rapidly identify the correct stroke type could help the practitioners in deciding stroke type specific treatment, thereby improving the management of stroke. This chapter gives an update on all the diagnostic test studies conducted to determine potential blood-based protein biomarkers to diagnose and differentiate ischemic stroke from hemorrhagic stroke, stroke mimics, transient ischemic attack, and mixed cases of ischemic stroke with hemorrhagic transformation.

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Authors and Affiliations

  1. Department of Neurology, All India Institute of Medical Sciences, New Delhi, India

    Deepti Vibha

  2. Department of Neurology, All India Institute of Medical Sciences, New Delhi, India

    Shubham Misra

Authors
  1. Deepti Vibha
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  2. Shubham Misra
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Editor information

Editors and Affiliations

  1. Department of Anatomy, University of Otago, Dunedin, New Zealand

    Philip V. Peplow

  2. Physical Chemistry and Applied Spectroscopy, Chemistry Division, Los Alamos National Lab, Los Alamos, NM, USA

    Bridget Martinez

  3. Brain Biomarkers Research Lab, Emory Decatur Hospital, Emory Healthcare, Decatur, GA, USA

    Svetlana A. Dambinova

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Vibha, D., Misra, S. (2020). Blood Biomarkers for Stroke Differentiation. In: Peplow, P.V., Martinez, B., Dambinova, S.A. (eds) Stroke Biomarkers. Neuromethods, vol 147. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9682-7_6

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  • DOI: https://doi.org/10.1007/978-1-4939-9682-7_6

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-9681-0

  • Online ISBN: 978-1-4939-9682-7

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