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Behavioral Genetic Studies in Rats

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Rat Genomics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2018))

Abstract

In this chapter, we briefly review the use of rats as a genetic model for the study of behavior. Rats were the first mammalian species used for genetic and biological research. Since the development of the first inbred rat strain in 1909, more than 700 unique inbred and outbred rat lines have been generated. Although rats have been somewhat eclipsed by mice in the last few decades, a renewed appreciation of the advantages of rats for behavioral and other types of research is upon us. We briefly review the pertinent characteristics of the rat and highlight the key advantages of using the rat to examine behavioral phenotypes.

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Author information

Authors and Affiliations

  1. Department of Psychiatry, University of California San Diego, La Jolla, CA, USA

    Yangsu Ren & Abraham A. Palmer

  2. Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA

    Abraham A. Palmer

Authors
  1. Yangsu Ren
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  2. Abraham A. Palmer
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Corresponding author

Correspondence to Abraham A. Palmer .

Editor information

Editors and Affiliations

  1. Department of Biomedical Engineering, Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA

    G. Thomas Hayman

  2. Department of Biomedical Engineering, Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA

    Jennifer R. Smith

  3. Department of Physiology, Rat Genome Database, Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, USA

    Melinda R. Dwinell

  4. Department of Biomedical Engineering, Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA

    Mary Shimoyama

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Ren, Y., Palmer, A.A. (2019). Behavioral Genetic Studies in Rats. In: Hayman, G., Smith, J., Dwinell, M., Shimoyama, M. (eds) Rat Genomics. Methods in Molecular Biology, vol 2018. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9581-3_16

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  • DOI: https://doi.org/10.1007/978-1-4939-9581-3_16

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-9580-6

  • Online ISBN: 978-1-4939-9581-3

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