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Kidney Organogenesis pp 223–232Cite as

Analysis of the Teashirt Target Genes in Ureteric Bud Development

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1926))

Abstract

Microarrays and RNA-seq (RNA sequencing) are powerful techniques to assess transcript abundance in biological samples and to improve our understanding of the relationship between genotype and phenotype. Tshz3+/− heterozygous mouse is a model for a human 19q12 syndrome characterized by autistic traits and renal tract defects (Caubit et al., Nat Genet 48:1359–1369, 2016). To unravel renal tract pathological mechanisms, we took advantage of Tshz3 mouse and performed comparative genome-wide expression profiling on embryonic ureter and/or kidney.

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References

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Authors and Affiliations

  1. Aix Marseille University, CNRS, IBDM, Marseille, France

    Laurent Fasano, Irene Sanchez-Martin & Xavier Caubit

Authors
  1. Laurent Fasano
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  2. Irene Sanchez-Martin
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  3. Xavier Caubit
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Corresponding author

Correspondence to Laurent Fasano .

Editor information

Editors and Affiliations

  1. Biocenter Oulu, Laboratory of Developmental Biology, Oulu University, Oulu, Finland

    Seppo Vainio

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Fasano, L., Sanchez-Martin, I., Caubit, X. (2019). Analysis of the Teashirt Target Genes in Ureteric Bud Development. In: Vainio, S. (eds) Kidney Organogenesis. Methods in Molecular Biology, vol 1926. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-9021-4_18

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  • DOI: https://doi.org/10.1007/978-1-4939-9021-4_18

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-9020-7

  • Online ISBN: 978-1-4939-9021-4

  • eBook Packages: Springer Protocols

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