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Peptide-Mediated Biomimetic Regrowth of Human Enamel In Situ

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Odontogenesis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1922))

Abstract

Mimicking the dynamics of mineral loss and gain involved in dental caries formation can help us evaluate and compare the mineralization efficacy of different treatment agents used in enamel remineralization. Here, we offer an abridged study design outlining the preparation of tooth samples, creation of artificial dental lesions, application of a peptide, and characterization of the regrown enamel-like mineral layer.

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Acknowledgments

This research was supported by NIH-NIDCR R01 grants DE-13414 and DE-020099 and the USC Coulter Translational Partnership Program.

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Authors and Affiliations

  1. Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA

    Kaushik Mukherjee, Qichao Ruan & Janet Moradian-Oldak

  2. Ormco Corporation, Glendora, USA

    Qichao Ruan

  3. Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA

    Janet Moradian-Oldak

Authors
  1. Kaushik Mukherjee
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  2. Qichao Ruan
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  3. Janet Moradian-Oldak
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Corresponding author

Correspondence to Janet Moradian-Oldak .

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Editors and Affiliations

  1. School of Dentistry, University of Michigan, Ann Arbor, MI, USA

    Petros Papagerakis

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Mukherjee, K., Ruan, Q., Moradian-Oldak, J. (2019). Peptide-Mediated Biomimetic Regrowth of Human Enamel In Situ. In: Papagerakis, P. (eds) Odontogenesis. Methods in Molecular Biology, vol 1922. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-9012-2_13

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  • DOI: https://doi.org/10.1007/978-1-4939-9012-2_13

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-9011-5

  • Online ISBN: 978-1-4939-9012-2

  • eBook Packages: Springer Protocols

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