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Immune Tolerance and Rejection in Organ Transplantation

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Immunological Tolerance

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1899))

Abstract

In this chapter, we describe the history of transplantation, the multiple cell types, and mechanisms that are involved in rejection and tolerance of a transplanted organ, as well as summarize the common and promising new therapeutics used in transplant patients.

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Acknowledgments

The work from the authors’ own laboratory described in this review was supported by grants from The Wellcome Trust, Medical Research council, BBSRC, British Heart Foundation, and European Union through the ONE Study, Bio-DrIM and TRIAD projects. The authors would like to thank all members of TRIG past and present for their valuable contributions to the data reviewed herein. The authors have no conflict of interest.

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Authors and Affiliations

  1. Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, UK

    Jessica Stolp, Masaaki Zaitsu & Kathryn J. Wood

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  1. Jessica Stolp
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  2. Masaaki Zaitsu
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  3. Kathryn J. Wood
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Correspondence to Kathryn J. Wood .

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Editors and Affiliations

  1. Associate Professor in Stem Cell Biology and Regenerative Medicine, Research Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London (UCL), Royal Free Hospital, London, UK

    Ashleigh S. Boyd

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Stolp, J., Zaitsu, M., Wood, K.J. (2019). Immune Tolerance and Rejection in Organ Transplantation. In: Boyd, A. (eds) Immunological Tolerance. Methods in Molecular Biology, vol 1899. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8938-6_12

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  • DOI: https://doi.org/10.1007/978-1-4939-8938-6_12

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