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Retinal Fundus Imaging in Mouse Models of Retinal Diseases

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Retinal Degeneration

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1834))

Abstract

The development of in vivo retinal fundus imaging in mice has opened a new research horizon, not only in ophthalmic research. The ability to monitor the dynamics of vascular and cellular changes in pathological conditions, such as neovascularization or degeneration, longitudinally without the need to sacrifice the mouse, permits longer observation periods in the same animal. With the application of the high-resolution confocal scanning laser ophthalmoscopy in experimental mouse models, access to a large spectrum of imaging modalities in vivo is provided. Recently developed optical coherence tomography angiography allows even noninvasive in vivo blood flow analysis.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, University of Muenster Medical School, Muenster, Germany

    Anne F. Alex, Maged Alnawaiseh, Peter Heiduschka & Nicole Eter

Authors
  1. Anne F. Alex
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  2. Maged Alnawaiseh
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  3. Peter Heiduschka
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  4. Nicole Eter
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Corresponding author

Correspondence to Nicole Eter .

Editor information

Editors and Affiliations

  1. Institute of Human Genetics, University of Regensburg, Regensburg, Germany

    Bernhard H. F. Weber

  2. Department of Ophthalmology, University of Cologne, Cologne, Germany

    Thomas Langmann

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Alex, A.F., Alnawaiseh, M., Heiduschka, P., Eter, N. (2019). Retinal Fundus Imaging in Mouse Models of Retinal Diseases. In: Weber, B.H.F., Langmann, T. (eds) Retinal Degeneration. Methods in Molecular Biology, vol 1834. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-8669-9_17

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  • DOI: https://doi.org/10.1007/978-1-4939-8669-9_17

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-8668-2

  • Online ISBN: 978-1-4939-8669-9

  • eBook Packages: Springer Protocols

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