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A Fungal Protease Model to Interrogate Allergic Lung Immunity

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Book cover Type 2 Immunity

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1799))

Abstract

Allergic airway diseases (asthma and chronic rhinosinusitis) are among the most common of all human diseases in heavily industrialized societies. Animal models of asthma have provided remarkable insight into allergic disease pathogenesis and will continue to drive the discovery of new therapeutic insights. We provide in this chapter a detailed protocol for inducing allergic immunity in the lungs of mice using a purified fungal protease and include related protocols for assessing immune endpoints.

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References

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Author information

Authors and Affiliations

  1. Departments of Medicine, Baylor College of Medicine, Houston, TX, USA

    J. Morgan Knight, Evan Li, Cameron Landers, Jake Wheeler, Farrah Kheradmand & David B. Corry

  2. Departments of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA

    Hui-Ying Tung, Farrah Kheradmand & David B. Corry

  3. Departments of Biology of Inflammation Center, Baylor College of Medicine, Houston, TX, USA

    Farrah Kheradmand & David B. Corry

  4. Michael E. DeBakey VA Center for Translational Research on Inflammatory Diseases, Houston, TX, USA

    Farrah Kheradmand & David B. Corry

Authors
  1. J. Morgan Knight
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  2. Evan Li
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  3. Hui-Ying Tung
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  4. Cameron Landers
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  5. Jake Wheeler
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  6. Farrah Kheradmand
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  7. David B. Corry
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Corresponding author

Correspondence to David B. Corry .

Editor information

Editors and Affiliations

  1. Department of Biomedical Research, National Jewish Health, Denver, CO, USA

    R. Lee Reinhardt

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Morgan Knight, J. et al. (2018). A Fungal Protease Model to Interrogate Allergic Lung Immunity. In: Reinhardt, R. (eds) Type 2 Immunity. Methods in Molecular Biology, vol 1799. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-7896-0_1

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  • DOI: https://doi.org/10.1007/978-1-4939-7896-0_1

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-7895-3

  • Online ISBN: 978-1-4939-7896-0

  • eBook Packages: Springer Protocols

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