Abstract
Visualization of complex genetic systems can help efficiently communicate important design features and clearly illustrate overall structures. To aid in the creation of such diagrams, standards such as the Synthetic Biology Open Language Visual (SBOLv) have been established to ensure that specific symbols and shapes convey the same meaning for genetic parts across the field. Here, we describe several ways that the computational tool DNAplotlib can be used to automate the generation of SBOLv standard-compliant diagrams covering simple genetic designs to large libraries of genetic constructs.
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Acknowledgments
T.E.G. was supported by BrisSynBio, a BBSRC/EPSRC Synthetic Biology Research Centre (grant BB/L01386X/1). V.B. and D.O.R.D acknowledge funding from the EPSRC & BBSRC Centre for Doctoral Training in Synthetic Biology (grant EP/L016494/1). We also thank Mario di Bernardo and Nigel Savery for comments.
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Bartoli, V., Dixon, D.O.R., Gorochowski, T.E. (2018). Automated Visualization of Genetic Designs Using DNAplotlib. In: Braman, J. (eds) Synthetic Biology. Methods in Molecular Biology, vol 1772. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7795-6_22
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DOI: https://doi.org/10.1007/978-1-4939-7795-6_22
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