Stool DNA Integrity Method for Colorectal Cancer Detection

  • Claudia Rengucci
  • Giulia De Maio
  • Maura Menghi
  • Daniele Calistri
Part of the Methods in Molecular Biology book series (MIMB, volume 1765)


Fluorescence long DNA (FL-DNA) is a non-invasive and simple-to-perform stool DNA test. This assay consists of a qualitative and quantitative real-time PCR (RT PCR) analysis. FL-DNA has great potential in colorectal cancer (CRC) lesions detection used alone or in combination with the standard CRC screening tool: immunochemical fecal occult blood test (iFOBT).

Key words

FL-DNA CRC Stool DNA Colonocytes Screening 



This work was supported by Diatech Pharmacogenetics, Jesi (AN)—Italy.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Claudia Rengucci
    • 1
  • Giulia De Maio
    • 1
  • Maura Menghi
    • 2
  • Daniele Calistri
    • 1
  1. 1.Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCSMeldolaItaly
  2. 2.Diatech PharmacogeneticsJesiItaly

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