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A Primer for the Rat Genome Database (RGD)

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Book cover Eukaryotic Genomic Databases

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1757))

Abstract

The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.

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Acknowledgments

RGD is supported by the National Heart, Lung, and Blood Institute on behalf of the National Institutes of Health [HL64541].

Author information

Authors and Affiliations

  1. Department of Biomedical Engineering, Medical College of Wisconsin and Marquette University, Milwaukee, WI, USA

    Stanley J. F. Laulederkind, G. Thomas Hayman, Shur-Jen Wang, Jennifer R. Smith, Victoria Petri, Jeff De Pons, Marek A. Tutaj, Omid Ghiasvand, Monika Tutaj, Jyothi Thota & Mary Shimoyama

  2. Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, USA

    Matthew J. Hoffman & Melinda R. Dwinell

  3. Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA

    Matthew J. Hoffman & Melinda R. Dwinell

Authors
  1. Stanley J. F. Laulederkind
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  2. G. Thomas Hayman
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  3. Shur-Jen Wang
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  4. Jennifer R. Smith
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  5. Victoria Petri
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  6. Matthew J. Hoffman
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  7. Jeff De Pons
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  8. Marek A. Tutaj
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  9. Omid Ghiasvand
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  10. Monika Tutaj
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  11. Jyothi Thota
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  12. Melinda R. Dwinell
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  13. Mary Shimoyama
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Corresponding author

Correspondence to Stanley J. F. Laulederkind .

Editor information

Editors and Affiliations

  1. Group Systems Biology of Motor Proteins, Department of NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

    Martin Kollmar

Additional information

Dedication

We wish to dedicate this chapter to the memory of our colleague and longtime RGD curator Dr. Victoria Petri, who recently passed away. Her legacy lives on through the RGD Pathway Ontology and Pathway Diagrams that she created.

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Laulederkind, S.J.F. et al. (2018). A Primer for the Rat Genome Database (RGD). In: Kollmar, M. (eds) Eukaryotic Genomic Databases. Methods in Molecular Biology, vol 1757. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7737-6_8

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  • DOI: https://doi.org/10.1007/978-1-4939-7737-6_8

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7736-9

  • Online ISBN: 978-1-4939-7737-6

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