Macroscopic Assessment and Cut Up of Endoscopic Resection Specimens for Early Esophageal Glandular Malignancies

  • Benjamin M. Allanson
  • M. Priyanthi Kumarasinghe
Part of the Methods in Molecular Biology book series (MIMB, volume 1756)


Pathological assessment of tissue is the gold standard for diagnosis and staging of neoplasia and provides key prognostic information for clinical management. Proper macroscopic assessment and cut-up technique is essential to ensure that the overall assessment is correct and reproducible. Endoscopic mucosal resection is a technique used for removing early neoplastic glandular lesions of the esophagus at the level of submucosa. Here, we describe the macroscopic assessment and dissection techniques used for the routine handling of endoscopic mucosal resection specimens in the clinical laboratory.

Key words

Esophageal adenocarcinoma Endoscopic mucosal resection Macroscopic Cut up Early stage cancer 


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Copyright information

© Springer Science+Business Media, LLC 2018

Authors and Affiliations

  • Benjamin M. Allanson
    • 1
  • M. Priyanthi Kumarasinghe
    • 2
    • 3
  1. 1.Department of Tissue Pathology and Diagnostic OncologyRoyal Prince Alfred HospitalCamperdownAustralia
  2. 2.PathWest Laboratory MedicineQueen Elizabeth II Medical CentreNedlandsAustralia
  3. 3.School of Pathology and Laboratory MedicineUniversity of Western AustraliaCrawleyAustralia

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