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Mouse Retinal Phenotyping pp 41–59Cite as

Modeling Retinal Diseases Using Genetic Approaches in Mice

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1753))

Abstract

Genetic mouse models mimicking human diseases have been developed and utilized for retinal research in various topics, involving anatomy, physiology, biochemistry, and pathology. The main reasons why mouse models are important for retinal research include that rodents share a key retinal homology with humans and that genetic manipulation is relatively easily applicable for mice. Here, we describe genetic mouse models, which are categorized with functions in the retina and relationship with human diseases.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH, USA

    Akiko Maeda

  2. Research Division, Kobe Research Institute, HEALIOS K.K., Kobe, Japan

    Tadao Maeda

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  1. Akiko Maeda
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  2. Tadao Maeda
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Editors and Affiliations

  1. Department of Ophthalmology, University Hospital Schleswig-Holstein, Kiel, Germany

    Naoyuki Tanimoto

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Maeda, A., Maeda, T. (2018). Modeling Retinal Diseases Using Genetic Approaches in Mice. In: Tanimoto, N. (eds) Mouse Retinal Phenotyping. Methods in Molecular Biology, vol 1753. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7720-8_3

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  • DOI: https://doi.org/10.1007/978-1-4939-7720-8_3

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7719-2

  • Online ISBN: 978-1-4939-7720-8

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