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Biomarkers for Preclinical Alzheimer’s Disease pp 45–62Cite as

The Dimensional Structure of Subjective Cognitive Decline

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Part of the book series: Neuromethods ((NM,volume 137))

Abstract

The self-experienced persistent decline in one’s cognitive abilities in comparison with a previously normal status is referred to as subjective cognitive decline (SCD). During the last decades, evidence has emerged about the close relationship between SCD and incident cognitive impairment to such an extent that SCD is currently considered as a very early marker of future dementia. Here, we first discuss the strengths and the weaknesses of this concept, and then we describe a procedure to measure SCD accurately. Our goal is to provide the reader with specific guidelines on how to assess and classify individuals in terms of SCD in order to identify individuals at high risk of developing cognitive impairment.

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Author information

Authors and Affiliations

  1. Alzheimer Disease Research Unit, CIEN Foundation, Carlos III Institute of Health, Queen Sofía Foundation Alzheimer Center, Madrid, Spain

    Miguel A. Fernández-Blázquez, Marina Ávila-Villanueva & Miguel Medina

  2. CIBERNED (Network Center for Biomedical Research in Neurodegenerative Diseases), Universidad Autónoma de Madrid, Madrid, Spain

    Miguel Medina

Authors
  1. Miguel A. Fernández-Blázquez
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  2. Marina Ávila-Villanueva
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  3. Miguel Medina
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Corresponding author

Correspondence to Miguel A. Fernández-Blázquez .

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Editors and Affiliations

  1. Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany

    Robert Perneczky

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Fernández-Blázquez, M.A., Ávila-Villanueva, M., Medina, M. (2018). The Dimensional Structure of Subjective Cognitive Decline. In: Perneczky, R. (eds) Biomarkers for Preclinical Alzheimer’s Disease. Neuromethods, vol 137. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7674-4_3

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  • DOI: https://doi.org/10.1007/978-1-4939-7674-4_3

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7673-7

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