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Extracellular Recording Approaches pp 225–247Cite as

Recording Extracellular Activity in the Developing Cerebellum of Behaving Rats

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Part of the book series: Neuromethods ((NM,volume 134))

Abstract

The in vivo extracellular activity of the cerebellum has been intensively investigated in adult animals to understand its roles in learning and memory and sensorimotor integration. Here we describe a method for studying extracellular activity in the cerebellum of unanesthetized, behaving infant rodents over the first 2 postnatal weeks, a time of substantial cerebellar circuit development. The study of extracellular activity during cerebellar development in behaving infants provides a unique opportunity to relate neural activity not only to cerebellar circuit development but to behavioral development as well. We propose that studying extracellular neural activity in the developing cerebellum provides a model system for examining the complex interactions between behavior and neural activity and how they contribute together to functional neural circuit development.

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Author information

Authors and Affiliations

  1. Department of Psychological & Brain Sciences, University of Iowa, Iowa City, IA, USA

    Greta Sokoloff & Mark S. Blumberg

  2. DeLTA Center, University of Iowa, Iowa City, IA, USA

    Greta Sokoloff & Mark S. Blumberg

  3. Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, IA, USA

    Mark S. Blumberg

  4. Department of Biology, University of Iowa, Iowa City, IA, USA

    Mark S. Blumberg

Authors
  1. Greta Sokoloff
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  2. Mark S. Blumberg
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Corresponding author

Correspondence to Greta Sokoloff .

Editor information

Editors and Affiliations

  1. Department of Pathology & Immunology and Neuroscience, Baylor College of Medicine, Houston, Texas, USA

    Roy V. Sillitoe

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Sokoloff, G., Blumberg, M.S. (2018). Recording Extracellular Activity in the Developing Cerebellum of Behaving Rats. In: Sillitoe, R. (eds) Extracellular Recording Approaches. Neuromethods, vol 134. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7549-5_12

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  • DOI: https://doi.org/10.1007/978-1-4939-7549-5_12

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7548-8

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