Introduction to MRI Physics

Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1718)

Abstract

Magnetic resonance imaging (MRI) is an imaging technique derived from radiofrequency (RF) signals of proton that are magnetized by a strong magnetic field. These protons typically originate from water, fat, or metabolites. The application of RF pulses is used to excite the magnetization, whereas pulsed magnetic field gradients are used to provide spatial localization. This chapter describes the fundamental principles giving rise to MR images. Furthermore, the connection between relaxation and image contrast is discussed.

Key words

Pulse sequences Encoding k-Space Relaxation Contrast 

References

  1. 1.
    Ardenkjær-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, Lerche MH, Servin R, Thaning M, Golman K (2003) Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR. Proc Natl Acad Sci 100(18):10158–10163CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Golman K, Lerche M, Pehrson R, Ardenkjaer-Larsen JH (2006) Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis. Cancer Res 66(22):10855–10860CrossRefPubMedGoogle Scholar
  3. 3.
    Rabi II, Zacharias JR, Millman S, Kusch P (1938) A new method of measuring nuclear magnetic moment. Phys Rev 53(4):318CrossRefGoogle Scholar
  4. 4.
    Bloch F (1946) Nuclear induction. Phys Rev 70(7–8):460CrossRefGoogle Scholar
  5. 5.
    Damadian R (1971) Tumor detection by nuclear magnetic resonance. Science 171(3976):1151–1153CrossRefPubMedGoogle Scholar
  6. 6.
    Lauterbur PC (1973) Image formation by induced local interactions. Examples employing nuclear magnetic resonance. Nature 242:190–191CrossRefGoogle Scholar
  7. 7.
    Pykett I, Rosen B (1983) Nuclear magnetic resonance: in vivo proton chemical shift imaging. Work in progress. Radiology 149(1):197–201CrossRefPubMedGoogle Scholar
  8. 8.
    Mansfield P (1984) Spatial mapping of the chemical shift in NMR. Magn Reson Med 1(3):370–386CrossRefPubMedGoogle Scholar
  9. 9.
    Posse S, DeCarli C, Le Bihan D (1994) Three-dimensional echo-planar MR spectroscopic imaging at short echo times in the human brain. Radiology 192(3):733–738CrossRefPubMedGoogle Scholar
  10. 10.
    Hahn EL (1950) Spin echoes. Phys Rev 80(4):580CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2018

Authors and Affiliations

  1. 1.Department of Cancer Imaging and MetabolismH. Lee Moffitt Cancer Center & Research InstituteTampaUSA

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