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Hemostasis and Thrombosis pp 349–367Cite as

Assessment of Platelet Function in Whole Blood by Flow Cytometry

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1646))

Abstract

Evaluation of platelet function is important for understanding the physiology of hemostasis and thrombosis and is utilized in clinical practice to diagnose inherited and acquired platelet bleeding disorders. Flow cytometry is a powerful tool for rapid evaluation of multiple functional properties of large number of platelets in whole blood and offers many advantages over other traditional methods. Attention to pre-analytical factors is required to ensure biologically valid and robust results.

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Acknowledgments

The author would like to thank Dr. Gabrielle Pennings from ANZAC Research Institute, at the University of Sydney, Sydney, for the helpful suggestions.

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Authors and Affiliations

  1. Deparments of Clinical and Laboratory Haematology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, NSW, 2145, Australia

    Leonardo Pasalic

  2. Sydney Centres for Thrombosis and Haemostasis, Westmead, NSW, Australia

    Leonardo Pasalic

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  1. Leonardo Pasalic
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Correspondence to Leonardo Pasalic .

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Editors and Affiliations

  1. Department of Haematology, Sydney Centres for Thrombosis and Haemostasis, Institute of Clinical Pathology and Medical Research (ICPMR), NSW Health Pathology, Westmead Hospital, Westmead, New South Wales, Australia

    Emmanuel J. Favaloro

  2. Section of Clinical Biochemistry, University of Verona, Verona, Italy

    Giuseppe Lippi

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Pasalic, L. (2017). Assessment of Platelet Function in Whole Blood by Flow Cytometry. In: Favaloro, E., Lippi, G. (eds) Hemostasis and Thrombosis. Methods in Molecular Biology, vol 1646. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7196-1_27

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  • DOI: https://doi.org/10.1007/978-1-4939-7196-1_27

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7194-7

  • Online ISBN: 978-1-4939-7196-1

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