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From Genes to Networks: Characterizing Gene-Regulatory Interactions in Plants

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Book cover Plant Gene Regulatory Networks

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1629))

Abstract

Plants, like other eukaryotes, have evolved complex mechanisms to coordinate gene expression during development, environmental response, and cellular homeostasis. Transcription factors (TFs), accompanied by basic cofactors and posttranscriptional regulators, are key players in gene-regulatory networks (GRNs). The coordinated control of gene activity is achieved by the interplay of these factors and by physical interactions between TFs and DNA. Here, we will briefly outline recent technological progress made to elucidate GRNs in plants. We will focus on techniques that allow us to characterize physical interactions in GRNs in plants and to analyze their regulatory consequences. Targeted manipulation allows us to test the relevance of specific gene-regulatory interactions. The combination of genome-wide experimental approaches with mathematical modeling allows us to get deeper insights into key-regulatory interactions and combinatorial control of important processes in plants.

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Acknowledgements

The authors wish to thank the Alexander-von-Humboldt foundation and the BMBF for support. We apologize to all authors whose work could not be cited due to space constraints.

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Authors and Affiliations

  1. Department for Plant Cell and Molecular Biology, Institute for Biology, Humboldt-Universität zu Berlin, 10115, Berlin, Germany

    Kerstin Kaufmann & Dijun Chen

  2. Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany

    Dijun Chen

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  1. Kerstin Kaufmann
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  2. Dijun Chen
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Correspondence to Kerstin Kaufmann .

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Editors and Affiliations

  1. Department for Plant Cell and Molecular Biology, Institute for Biology, Humboldt-Universität zu Berlin, Berlin, Germany

    Kerstin Kaufmann

  2. Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany

    Bernd Mueller-Roeber

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Kaufmann, K., Chen, D. (2017). From Genes to Networks: Characterizing Gene-Regulatory Interactions in Plants. In: Kaufmann, K., Mueller-Roeber, B. (eds) Plant Gene Regulatory Networks. Methods in Molecular Biology, vol 1629. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7125-1_1

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  • DOI: https://doi.org/10.1007/978-1-4939-7125-1_1

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  • Print ISBN: 978-1-4939-7124-4

  • Online ISBN: 978-1-4939-7125-1

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