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Proteomics Analysis of Circulating Serum Exosomes

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Serum/Plasma Proteomics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1619))

Abstract

Proteomics characterization of biofluids, such as urine and plasma, has been explored for the discovery of predictive, prognostic, and mechanistic biomarkers of diseases and tissue injury. Here we describe comprehensive characterization of protein cargos from cell-derived secreted vesicles (extracellular vesicles or exosome) for biomarker discovery using the mass spectrometry-based technology.

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Author information

Authors and Affiliations

  1. Herbert Irving Comprehensive Cancer Center, Proteomics Shared Resource, Columbia University Medical Center, New York, NY, 10032, USA

    Antonius Koller, Purvi Patel, Jenny Kim Kim & Emily I. Chen

  2. Department of Pharmacology, Columbia University Medical Center, New York, NY, 10032, USA

    Emily I. Chen

Authors
  1. Antonius Koller
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  2. Purvi Patel
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  3. Jenny Kim Kim
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  4. Emily I. Chen
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Corresponding author

Correspondence to Emily I. Chen .

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

    David W. Greening

  2. Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

    Richard J. Simpson

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Koller, A., Patel, P., Kim, J.K., Chen, E.I. (2017). Proteomics Analysis of Circulating Serum Exosomes. In: Greening, D., Simpson, R. (eds) Serum/Plasma Proteomics. Methods in Molecular Biology, vol 1619. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7057-5_17

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  • DOI: https://doi.org/10.1007/978-1-4939-7057-5_17

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7056-8

  • Online ISBN: 978-1-4939-7057-5

  • eBook Packages: Springer Protocols

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