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Ultrastructure of Immune Synapses

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The Immune Synapse

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1584))

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Abstract

The immunological synapse is a critical event for immune response development. The use of planar supported bilayers as surrogate antigen-presenting cells is a useful tool to study this phenomenon. Here we describe electron microscopy methods and approaches to expand our knowledge of the events taking place during the initial phases of T cell activation after antigen recognition at the nanometer scale.

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References

  1. Dustin ML, Starr T, Varma R, Thomas VK (2007) Supported planar bilayers for study of the immunological synapse. Curr Protoc Immunol 18:13

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Author information

Authors and Affiliations

  1. Department of Physiology, University of Bern, Hochschulstrasse 4, 3012, Bern, Switzerland

    Jaime Llodrá

Authors
  1. Jaime Llodrá
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Correspondence to Jaime Llodrá .

Editor information

Editors and Affiliations

  1. Department of Life sciences, University of Siena, Siena, Siena, Italy

    Cosima T. Baldari

  2. University of Oxford, Kennedy Institute of Rheumatology, Headington, Oxford, United Kingdom

    Michael L. Dustin

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Llodrá, J. (2017). Ultrastructure of Immune Synapses. In: Baldari, C., Dustin, M. (eds) The Immune Synapse. Methods in Molecular Biology, vol 1584. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6881-7_24

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  • DOI: https://doi.org/10.1007/978-1-4939-6881-7_24

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6879-4

  • Online ISBN: 978-1-4939-6881-7

  • eBook Packages: Springer Protocols

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