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Generation of Janus Molecularly Imprinted Polymer Particles

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Synthetic Antibodies

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1575))

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Abstract

Janus particles, which have two or more distinct physical surfaces, provide a number of potential applications in many fields. However, it is difficult to selectively load chemical or biological components onto the Janus particles. Here, the approach utilizing molecular imprinting and Pickering emulsion technologies for the synthesis of molecularly imprinted polymer (MIP)-based Janus particles (which showed high affinity to the targets) is described stepwise. As self-propelled microengines possessing specific molecular recognition ability, Janus molecularly imprinted polymer particles show high potential for specific and well-controlled drug delivery.

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Acknowledgment

This work was supported by the Fundamental Research Funds for the Central Universities in China (2015YGYL024).

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Correspondence to Xiantao Shen .

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Shen, X., Huang, C., Ye, L. (2017). Generation of Janus Molecularly Imprinted Polymer Particles. In: Tiller, T. (eds) Synthetic Antibodies. Methods in Molecular Biology, vol 1575. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6857-2_22

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  • DOI: https://doi.org/10.1007/978-1-4939-6857-2_22

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6855-8

  • Online ISBN: 978-1-4939-6857-2

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