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Proteome Bioinformatics pp 101–107Cite as

Proteotypic Peptides and Their Applications

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1549))

Abstract

Recent advances in mass spectrometry based proteomic techniques and publicly available large proteomic repositories are being exploited to characterize the proteome of multiple organisms. While humongous amount of proteomic data is being acquired and analyzed, many biological questions still remain unanswered. Proteotypic peptides which uniquely represent target proteins or a protein isoform are used as an alternative strategy for protein identification in the field of immunological methods and targeted proteomic techniques. Using different computational approaches, resources and techniques used in the identification of proteotypic peptides of target proteins is discussed here.

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Authors and Affiliations

  1. Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia

    Shivakumar Keerthikumar & Suresh Mathivanan

Authors
  1. Shivakumar Keerthikumar
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  2. Suresh Mathivanan
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Correspondence to Shivakumar Keerthikumar .

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Editors and Affiliations

  1. Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

    Shivakumar Keerthikumar

  2. Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

    Suresh Mathivanan

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Keerthikumar, S., Mathivanan, S. (2017). Proteotypic Peptides and Their Applications. In: Keerthikumar, S., Mathivanan, S. (eds) Proteome Bioinformatics. Methods in Molecular Biology, vol 1549. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6740-7_8

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  • DOI: https://doi.org/10.1007/978-1-4939-6740-7_8

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6738-4

  • Online ISBN: 978-1-4939-6740-7

  • eBook Packages: Springer Protocols

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