Abstract
Transcranial magnetic stimulation is a technique that allows the induction of electrical current in the superficial brain tissue, by means of a rapidly changing magnetic field. It is a noninvasive technique which may be safely applied to awake and collaborating humans. The biological effects of transcranial magnetic stimulation can be classified as immediate, consisting of action potentials, and delayed, consisting of variably lasting changes in the excitability of neurons, outlasting stimulation itself. Accordingly, the impact of TMS on behavior can be generally categorized as “online” or “offline.” TMS produces behavioral changes by manipulating the firing characteristics of neurons. As a consequence, TMS may be used to establish causal relationships between brain and behavior. The direct effects of TMS have a limited spatial distribution, in the order of 1–2 cm, thus making it an optimal tool for hemispheric localization of brain functions. TMS has been applied to the study of lateralization of brain functions in humans in multiple domains such as language, spatial attention, or executive functions.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsAbbreviations
- CSP:
-
Cortical silent period
- DLPFC:
-
Dorsolateral prefrontal cortex
- EEG:
-
Electroencephalography
- EMG:
-
Electromyography
- ICF:
-
Intracortical facilitation
- ICI:
-
Intracortical inhibition
- ISI:
-
Inter-stimulus interval
- ISP:
-
Ipsilateral silent period
- MEP:
-
Motor evoked potential
- PAS:
-
Paired associative stimulation
- rTMS:
-
Repetitive transcranial magnetic stimulation
- TBS:
-
Theta-burst stimulation
- TES:
-
Transcranial electrical stimulation
- TMS:
-
Transcranial magnetic stimulation
References
Fritsch GT, Hitzig E (1870) Ueber die elektrische Erregbarkeit des Grosshirns. In: Archiv für Anatomie, Physiologie und wissenschaftliche Medicin. G. Eichler, Berlin, pp 300–332
Cushing H (1909) A note upon the faradic stimulation of the post-central gyrus in conscious patients. Brain 32:44–53
Foerster O (1936) Motorische Felder und Bahnen. In: Bumke H, Foerster O (eds) Handbuch der Neurologie IV. Springer, Berlin, pp 49–56
Penfield W, Boldrey E (1937) Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 60:389–443
Marsden CD, Merton PA, Morton HB (1983) Direct electrical stimulation of corticospinal pathways through the intact scalp in human subjects. Adv Neurol 39:387–391
Merton PA et al (1982) Scope of a technique for electrical stimulation of human brain, spinal cord, and muscle. Lancet 2(8298):597–600
Barker AT, Jalinous R, Freeston IL (1985) Non-invasive magnetic stimulation of human motor cortex. Lancet 1(8437):1106–1107
Miranda PC (2013) Physics of effects of transcranial brain stimulation. Handb Clin Neurol 116:353–366
Roth Y et al (2007) Three-dimensional distribution of the electric field induced in the brain by transcranial magnetic stimulation using figure-8 and deep H-coils. J Clin Neurophysiol 24(1):31–38
Rudiak D, Marg E (1994) Finding the depth of magnetic brain stimulation: a re-evaluation. Electroencephalogr Clin Neurophysiol 93(5):358–371
Deng ZD, Lisanby SH, Peterchev AV (2013) Electric field depth-focality tradeoff in transcranial magnetic stimulation: simulation comparison of 50 coil designs. Brain Stimul 6(1):1–13
Basser PJ, Wijesinghe RS, Roth BJ (1992) The activating function for magnetic stimulation derived from a three-dimensional volume conductor model. IEEE Trans Biomed Eng 39(11):1207–1210
Basser PJ, Roth BJ (1991) Stimulation of a myelinated nerve axon by electromagnetic induction. Med Biol Eng Comput 29(3):261–268
Roth BJ, Basser PJ (1990) A model of the stimulation of a nerve fiber by electromagnetic induction. IEEE Trans Biomed Eng 37(6):588–597
Nagarajan SS, Durand DM, Warman EN (1993) Effects of induced electric fields on finite neuronal structures: a simulation study. IEEE Trans Biomed Eng 40(11):1175–1188
Silva S, Basser PJ, Miranda PC (2008) Elucidating the mechanisms and loci of neuronal excitation by transcranial magnetic stimulation using a finite element model of a cortical sulcus. Clin Neurophysiol 119(10):2405–2413
Abdeen MA, Stuchly MA (1994) Modeling of magnetic field stimulation of bent neurons. IEEE Trans Biomed Eng 41(11):1092–1095
Ravazzani P et al (1996) Magnetic stimulation of the nervous system: induced electric field in unbounded, semi-infinite, spherical, and cylindrical media. Ann Biomed Eng 24(5):606–616
Ruohonen J, Ravazzani P, Grandori F (1995) An analytical model to predict the electric field and excitation zones due to magnetic stimulation of peripheral nerves. IEEE Trans Biomed Eng 42(2):158–161
Hsu KH, Durand DM (2000) Prediction of neural excitation during magnetic stimulation using passive cable models. IEEE Trans Biomed Eng 47(4):463–471
Hsu KH, Nagarajan SS, Durand DM (2003) Analysis of efficiency of magnetic stimulation. IEEE Trans Biomed Eng 50(11):1276–1285
Rotem A, Moses E (2006) Magnetic stimulation of curved nerves. IEEE Trans Biomed Eng 53(3):414–420
Salvador R et al (2011) Determining which mechanisms lead to activation in the motor cortex: a modeling study of transcranial magnetic stimulation using realistic stimulus waveforms and sulcal geometry. Clin Neurophysiol 122(4):748–758
Rotem A, Moses E (2008) Magnetic stimulation of one-dimensional neuronal cultures. Biophys J 94(12):5065–5078
Pashut T et al (2014) Patch-clamp recordings of rat neurons from acute brain slices of the somatosensory cortex during magnetic stimulation. Front Cell Neurosci 8:145
Patton HD, Amassian VE (1954) Single and multiple-unit analysis of cortical stage of pyramidal tract activation. J Neurophysiol 17(4):345–363
Rusu CV et al (2014) A model of TMS-induced I-waves in motor cortex. Brain Stimul 7(3):401–414
Moliadze V et al (2005) Paired-pulse transcranial magnetic stimulation protocol applied to visual cortex of anaesthetized cat: effects on visually evoked single-unit activity. J Physiol 566(Pt 3):955–965
Moliadze V et al (2003) Effect of transcranial magnetic stimulation on single-unit activity in the cat primary visual cortex. J Physiol 553(Pt 2):665–679
Allen EA et al (2007) Transcranial magnetic stimulation elicits coupled neural and hemodynamic consequences. Science 317(5846):1918–1921
Kozyrev V, Eysel UT, Jancke D (2014) Voltage-sensitive dye imaging of transcranial magnetic stimulation-induced intracortical dynamics. Proc Natl Acad Sci U S A 111(37):13553–13558
Kim T et al (2015) Transcranial magnetic stimulation changes response selectivity of neurons in the visual cortex. Brain Stimul 8(3):613–623
Meyer BU et al (1991) Magnetic stimuli applied over motor and visual cortex: influence of coil position and field polarity on motor responses, phosphenes, and eye movements. Electroencephalogr Clin Neurophysiol Suppl 43:121–134
Amassian VE et al (1989) Suppression of visual perception by magnetic coil stimulation of human occipital cortex. Electroencephalogr Clin Neurophysiol 74(6):458–462
Beckers G, Homberg V (1991) Impairment of visual perception and visual short term memory scanning by transcranial magnetic stimulation of occipital cortex. Exp Brain Res 87(2):421–432
Walsh V, Rushworth M (1999) A primer of magnetic stimulation as a tool for neuropsychology. Neuropsychologia 37(2):125–135
Ruzzoli M et al (2011) The effect of TMS on visual motion sensitivity: an increase in neural noise or a decrease in signal strength? J Neurophysiol 106(1):138–143
Harris JA, Clifford CW, Miniussi C (2008) The functional effect of transcranial magnetic stimulation: signal suppression or neural noise generation? J Cogn Neurosci 20(4):734–740
Ruzzoli M, Marzi CA, Miniussi C (2010) The neural mechanisms of the effects of transcranial magnetic stimulation on perception. J Neurophysiol 103(6):2982–2989
Schwarzkopf DS, Silvanto J, Rees G (2011) Stochastic resonance effects reveal the neural mechanisms of transcranial magnetic stimulation. J Neurosci 31(9):3143–3147
Perini F et al (2012) Occipital transcranial magnetic stimulation has an activity-dependent suppressive effect. J Neurosci 32(36):12361–12365
Miniussi C, Ruzzoli M, Walsh V (2010) The mechanism of transcranial magnetic stimulation in cognition. Cortex 46(1):128–130
Theoret H et al (2003) Exploring paradoxical functional facilitation with TMS. Suppl Clin Neurophysiol 56:211–219
Silvanto J, Pascual-Leone A (2008) State-dependency of transcranial magnetic stimulation. Brain Topogr 21(1):1–10
Abrahamyan A et al (2011) Improving visual sensitivity with subthreshold transcranial magnetic stimulation. J Neurosci 31(9):3290–3294
Rahnev DA et al (2012) Direct injection of noise to the visual cortex decreases accuracy but increases decision confidence. J Neurophysiol 107(6):1556–1563
Abrahamyan A et al (2015) Low intensity TMS enhances perception of visual stimuli. Brain Stimul 8(6):1175–1182
Mulckhuyse M et al (2011) Enhanced visual perception with occipital transcranial magnetic stimulation. Eur J Neurosci 34(8):1320–1325
Yozbatiran N et al (2009) Safety and behavioral effects of high-frequency repetitive transcranial magnetic stimulation in stroke. Stroke 40(1):309–312
Voss M et al (2007) An improvement in perception of self-generated tactile stimuli following theta-burst stimulation of primary motor cortex. Neuropsychologia 45(12):2712–2717
Nowak DA et al (2005) High-frequency repetitive transcranial magnetic stimulation over the hand area of the primary motor cortex disturbs predictive grip force scaling. Eur J Neurosci 22(9):2392–2396
Mazzocchio R et al (1994) Effect of tonic voluntary activity on the excitability of human motor cortex. J Physiol 474(2):261–267
Baker SN, Olivier E, Lemon RN (1995) Task-related variation in corticospinal output evoked by transcranial magnetic stimulation in the macaque monkey. J Physiol 488(Pt 3):795–801
Massimini M et al (2005) Breakdown of cortical effective connectivity during sleep. Science 309(5744):2228–2232
Silvanto J et al (2008) Baseline cortical excitability determines whether TMS disrupts or facilitates behavior. J Neurophysiol 99(5):2725–2730
Cattaneo Z et al (2008) Using state-dependency of transcranial magnetic stimulation (TMS) to investigate letter selectivity in the left posterior parietal cortex: a comparison of TMS-priming and TMS-adaptation paradigms. Eur J Neurosci 28(9):1924–1929
Silvanto J, Muggleton NG (2008) Testing the validity of the TMS state-dependency approach: targeting functionally distinct motion-selective neural populations in visual areas V1/V2 and V5/MT+. Neuroimage 40(4):1841–1848
Cattaneo L, Sandrini M, Schwarzbach J (2010) State-dependent TMS reveals a hierarchical representation of observed acts in the temporal, parietal, and premotor cortices. Cereb Cortex 20(9):2252–2258
Cattaneo L et al (2011) One’s motor performance predictably modulates the understanding of others’ actions through adaptation of premotor visuo-motor neurons. Soc Cogn Affect Neurosci 6(3):301–310
Jacquet PO, Avenanti A (2015) Perturbing the action observation network during perception and categorization of actions’ goals and grips: state-dependency and virtual lesion TMS effects. Cereb Cortex 25(3):598–608
Davare M et al (2009) Ventral premotor to primary motor cortical interactions during object-driven grasp in humans. Cortex 45(9):1050–1057
Baumer T et al (2009) Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest—a bifocal TMS study. Clin Neurophysiol 120(9):1724–1731
Koch G et al (2008) Functional interplay between posterior parietal and ipsilateral motor cortex revealed by twin-coil transcranial magnetic stimulation during reach planning toward contralateral space. J Neurosci 28(23):5944–5953
Cattaneo L, Barchiesi G (2011) Transcranial magnetic mapping of the short-latency modulations of corticospinal activity from the ipsilateral hemisphere during rest. Front Neural Circuits 5:14
Maule F et al (2015) Haptic working memory for grasping: the role of the parietal operculum. Cereb Cortex 25:528–537
Parmigiani S, Barchiesi G, Cattaneo L (2015) The dorsal premotor cortex exerts a powerful and specific inhibitory effect on the ipsilateral corticofacial system: a dual-coil transcranial magnetic stimulation study. Exp Brain Res 233(11):3253–3260
Ferbert A et al (1992) Interhemispheric inhibition of the human motor cortex. J Physiol 453:525–546
Tokimura H et al (2000) Short latency inhibition of human hand motor cortex by somatosensory input from the hand. J Physiol 523(Pt 2):503–513
Kujirai T et al (1993) Corticocortical inhibition in human motor cortex. J Physiol 471:501–519
Lee L et al (2003) Acute remapping within the motor system induced by low-frequency repetitive transcranial magnetic stimulation. J Neurosci 23(12):5308–5318
Gangitano M et al (2002) Modulation of input-output curves by low and high frequency repetitive transcranial magnetic stimulation of the motor cortex. Clin Neurophysiol 113(8):1249–1257
Touge T et al (2001) Are the after-effects of low-frequency rTMS on motor cortex excitability due to changes in the efficacy of cortical synapses? Clin Neurophysiol 112(11):2138–2145
Chen R et al (1997) Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology 48(5):1398–1403
Heide G, Witte OW, Ziemann U (2006) Physiology of modulation of motor cortex excitability by low-frequency suprathreshold repetitive transcranial magnetic stimulation. Exp Brain Res 171(1):26–34
Quartarone A et al (2005) Distinct changes in cortical and spinal excitability following high-frequency repetitive TMS to the human motor cortex. Exp Brain Res 161(1):114–124
Pascual-Leone A et al (1994) Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex. Brain 117(Pt 4):847–858
Maeda F et al (2000) Interindividual variability of the modulatory effects of repetitive transcranial magnetic stimulation on cortical excitability. Exp Brain Res 133(4):425–430
Maeda F et al (2000) Modulation of corticospinal excitability by repetitive transcranial magnetic stimulation. Clin Neurophysiol 111(5):800–805
Peinemann A et al (2004) Long-lasting increase in corticospinal excitability after 1800 pulses of subthreshold 5 Hz repetitive TMS to the primary motor cortex. Clin Neurophysiol 115(7):1519–1526
Modugno N et al (2001) Motor cortex excitability following short trains of repetitive magnetic stimuli. Exp Brain Res 140(4):453–459
Wu T et al (2000) Lasting influence of repetitive transcranial magnetic stimulation on intracortical excitability in human subjects. Neurosci Lett 287(1):37–40
Di Lazzaro V et al (2005) Theta-burst repetitive transcranial magnetic stimulation suppresses specific excitatory circuits in the human motor cortex. J Physiol 565(Pt 3):945–950
Huang YZ et al (2005) Theta burst stimulation of the human motor cortex. Neuron 45(2):201–206
Stefan K et al (2000) Induction of plasticity in the human motor cortex by paired associative stimulation. Brain 123(Pt 3):572–584
Cattaneo L, Barchiesi G (2015) The auditory space in the motor system. Neuroscience 304:81–89
Avenanti A et al (2009) Freezing or escaping? Opposite modulations of empathic reactivity to the pain of others. Cortex 45(9):1072–1077
Glenberg AM et al (2008) Processing abstract language modulates motor system activity. Q J Exp Psychol (Hove) 61(6):905–919
Barchiesi G, Cattaneo L (2013) Early and late motor responses to action observation. Soc Cogn Affect Neurosci 8(6):711–719
Cattaneo Z et al (2009) The mental number line modulates visual cortical excitability. Neurosci Lett 462(3):253–256
Bestmann S et al (2007) Spatial attention changes excitability of human visual cortex to direct stimulation. Curr Biol 17(2):134–139
Ubaldi S, Barchiesi G, Cattaneo L (2015) Bottom-up and top-down visuomotor responses to action observation. Cereb Cortex 25(4):1032–1041
Rossi S et al (2007) A real electro-magnetic placebo (REMP) device for sham transcranial magnetic stimulation (TMS). Clin Neurophysiol 118(3):709–716
Okamoto M et al (2004) Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10–20 system oriented for transcranial functional brain mapping. Neuroimage 21(1):99–111
Okamoto M, Dan I (2005) Automated cortical projection of head-surface locations for transcranial functional brain mapping. Neuroimage 26(1):18–28
Mills KR, Kimiskidis V (1996) Cortical and spinal mechanisms of facilitation to brain stimulation. Muscle Nerve 19(8):953–958
Koski L et al (2005) Normative data on changes in transcranial magnetic stimulation measures over a ten hour period. Clin Neurophysiol 116(9):2099–2109
Badawy RA et al (2012) Inter-session repeatability of cortical excitability measurements in patients with epilepsy. Epilepsy Res 98(2–3):182–186
Kimiskidis VK et al (2004) The repeatability of corticomotor threshold measurements. Neurophysiol Clin 34(6):259–266
Wassermann EM (2002) Variation in the response to transcranial magnetic brain stimulation in the general population. Clin Neurophysiol 113(7):1165–1171
Conforto AB et al (2004) Impact of coil position and electrophysiological monitoring on determination of motor thresholds to transcranial magnetic stimulation. Clin Neurophysiol 115(4):812–819
Mills KR, Nithi KA (1997) Corticomotor threshold to magnetic stimulation: normal values and repeatability. Muscle Nerve 20(5):570–576
Hanajima R et al (2007) Comparison of different methods for estimating motor threshold with transcranial magnetic stimulation. Clin Neurophysiol 118(9):2120–2122
Rossini PM et al (1994) Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol 91(2):79–92
Rossini PM et al (2015) Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee. Clin Neurophysiol 126(6):1071–1107
Stokes MG et al (2005) Simple metric for scaling motor threshold based on scalp-cortex distance: application to studies using transcranial magnetic stimulation. J Neurophysiol 94(6):4520–4527
Wassermann EM (1998) Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5–7, 1996. Electroencephalogr Clin Neurophysiol 108(1):1–16
Rossi S et al (2009) Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol 120(12):2008–2039
Kayser S et al (2013) Comparable seizure characteristics in magnetic seizure therapy and electroconvulsive therapy for major depression. Eur Neuropsychopharmacol 23(11):1541–1550
Lisanby SH et al (2003) Safety and feasibility of magnetic seizure therapy (MST) in major depression: randomized within-subject comparison with electroconvulsive therapy. Neuropsychopharmacology 28(10):1852–1865
Fierro B et al (2001) Timing of right parietal and frontal cortex activity in visuo-spatial perception: a TMS study in normal individuals. Neuroreport 12(11):2605–2607
Bagattini C et al (2015) No causal effect of left hemisphere hyperactivity in the genesis of neglect-like behavior. Neuropsychologia 72:12–21
Bonni S et al (2015) Role of the anterior temporal lobes in semantic representations: paradoxical results of a cTBS study. Neuropsychologia 76:163–169
Gough PM, Nobre AC, Devlin JT (2005) Dissociating linguistic processes in the left inferior frontal cortex with transcranial magnetic stimulation. J Neurosci 25(35):8010–8016
Devlin JT, Matthews PM, Rushworth MF (2003) Semantic processing in the left inferior prefrontal cortex: a combined functional magnetic resonance imaging and transcranial magnetic stimulation study. J Cogn Neurosci 15(1):71–84
Cattaneo Z et al (2010) The causal role of category-specific neuronal representations in the left ventral premotor cortex (PMv) in semantic processing. Neuroimage 49(3):2728–2734
Pobric G, Hamilton AF (2006) Action understanding requires the left inferior frontal cortex. Curr Biol 16(5):524–529
Aziz-Zadeh L et al (2002) Lateralization in motor facilitation during action observation: a TMS study. Exp Brain Res 144(1):127–131
Urgesi C et al (2007) Representation of body identity and body actions in extrastriate body area and ventral premotor cortex. Nat Neurosci 10(1):30–31
Aziz-Zadeh L et al (2005) Covert speech arrest induced by rTMS over both motor and nonmotor left hemisphere frontal sites. J Cogn Neurosci 17(6):928–938
Cattaneo L (2013) Language. Handb Clin Neurol 116:681–691
Rossi S et al (2006) Prefrontal and parietal cortex in human episodic memory: an interference study by repetitive transcranial magnetic stimulation. Eur J Neurosci 23(3):793–800
Kohler S et al (2004) Effects of left inferior prefrontal stimulation on episodic memory formation: a two-stage fMRI-rTMS study. J Cogn Neurosci 16(2):178–188
Innocenti I et al (2010) Event-related rTMS at encoding affects differently deep and shallow memory traces. Neuroimage 53(1):325–330
Broca P (1865) Sur le siège de la faculté du langage articulé. Bull Mém Soc Anthropol Paris 6(1):377–393
Pascual-Leone A, Gates JR, Dhuna A (1991) Induction of speech arrest and counting errors with rapid-rate transcranial magnetic stimulation. Neurology 41(5):697–702
Epstein CM et al (1999) Localization and characterization of speech arrest during transcranial magnetic stimulation. Clin Neurophysiol 110(6):1073–1079
Epstein CM et al (1996) Optimum stimulus parameters for lateralized suppression of speech with magnetic brain stimulation. Neurology 47(6):1590–1593
Epstein CM et al (2000) Repetitive transcranial magnetic stimulation does not replicate the Wada test. Neurology 55(7):1025–1027
Sidtis D, Canterucci G, Katsnelson D (2009) Effects of neurological damage on production of formulaic language. Clin Linguist Phon 23(4):270–284
Stewart L et al (2001) Transcranial magnetic stimulation produces speech arrest but not song arrest. Ann N Y Acad Sci 930:433–435
Soares JC, Mann JJ (1997) The anatomy of mood disorders—review of structural neuroimaging studies. Biol Psychiatry 41(1):86–106
Drevets WC (2000) Neuroimaging studies of mood disorders. Biol Psychiatry 48(8):813–829
Carpenter LL et al (2012) Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of acute treatment outcomes in clinical practice. Depress Anxiety 29(7):587–596
O'Reardon JP et al (2007) Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial. Biol Psychiatry 62(11):1208–1216
Janicak PG, Dokucu ME (2015) Transcranial magnetic stimulation for the treatment of major depression. Neuropsychiatr Dis Treat 11:1549–1560
Chen J et al (2013) Left versus right repetitive transcranial magnetic stimulation in treating major depression: a meta-analysis of randomised controlled trials. Psychiatry Res 210(3):1260–1264
Schutter DJ (2009) Antidepressant efficacy of high-frequency transcranial magnetic stimulation over the left dorsolateral prefrontal cortex in double-blind sham-controlled designs: a meta-analysis. Psychol Med 39(1):65–75
Haun DB et al (2010) Origins of spatial, temporal and numerical cognition: Insights from comparative psychology. Trends Cogn Sci 14(12):552–560
Pinel P et al (2001) Modulation of parietal activation by semantic distance in a number comparison task. Neuroimage 14(5):1013–1026
Piazza M et al (2007) A magnitude code common to numerosities and number symbols in human intraparietal cortex. Neuron 53(2):293–305
Gerstmann J (1940) Syndrome of finger agnosia, disorientation for right and left, agraphia and acalculia—local diagnostic value. Arch Neurol Psychiatry 44(2):398–408
Dormal V, Andres M, Pesenti M (2008) Dissociation of numerosity and duration processing in the left intraparietal sulcus: a transcranial magnetic stimulation study. Cortex 44(4):462–469
Cappelletti M et al (2007) rTMS over the intraparietal sulcus disrupts numerosity processing. Exp Brain Res 179(4):631–642
Knops A et al (2006) On the functional role of human parietal cortex in number processing: How gender mediates the impact of a ‘virtual lesion’ induced by rTMS. Neuropsychologia 44(12):2270–2283
Sandrini M, Rossini PM, Miniussi C (2004) The differential involvement of inferior parietal lobule in number comparison: a rTMS study. Neuropsychologia 42(14):1902–1909
Sasanguie D, Gobel SM, Reynvoet B (2013) Left parietal TMS disturbs priming between symbolic and non-symbolic number representations. Neuropsychologia 51(8):1528–1533
Gobel S, Walsh V, Rushworth MF (2001) The mental number line and the human angular gyrus. Neuroimage 14(6):1278–1289
Gobel SM et al (2006) Parietal rTMS distorts the mental number line: simulating ‘spatial’ neglect in healthy subjects. Neuropsychologia 44(6):860–868
Cohen Kadosh R et al (2007) Virtual dyscalculia induced by parietal-lobe TMS impairs automatic magnitude processing. Curr Biol 17(8):689–693
Cohen Kadosh R, Bien N, Sack AT (2012) Automatic and intentional number processing both rely on intact right parietal cortex: a combined FMRI and neuronavigated TMS study. Front Hum Neurosci 6:2
Andres M et al (2011) Role of distinct parietal areas in arithmetic: an fMRI-guided TMS study. Neuroimage 54(4):3048–3056
McCarthy G et al (1997) Face-specific processing in the human fusiform gyrus. J Cogn Neurosci 9(5):605–610
Damasio AR, Damasio H, Van Hoesen GW (1982) Prosopagnosia: anatomic basis and behavioral mechanisms. Neurology 32(4):331–341
Ilmoniemi RJ et al (1997) Neuronal responses to magnetic stimulation reveal cortical reactivity and connectivity. Neuroreport 8(16):3537–3540
Hofer S, Frahm J (2006) Topography of the human corpus callosum revisited—comprehensive fiber tractography using diffusion tensor magnetic resonance imaging. Neuroimage 32(3):989–994
Wahl M et al (2007) Human motor corpus callosum: topography, somatotopy, and link between microstructure and function. J Neurosci 27(45):12132–12138
Wassermann EM et al (1991) Effects of transcranial magnetic stimulation on ipsilateral muscles. Neurology 41(11):1795–1799
Giovannelli F et al (2009) Modulation of interhemispheric inhibition by volitional motor activity: an ipsilateral silent period study. J Physiol 587(Pt 22):5393–5410
Meyer BU, Roricht S, Woiciechowsky C (1998) Topography of fibers in the human corpus callosum mediating interhemispheric inhibition between the motor cortices. Ann Neurol 43(3):360–369
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer Science+Business Media LLC
About this protocol
Cite this protocol
Cattaneo, L. (2017). Transcranial Magnetic Stimulation. In: Rogers, L., Vallortigara, G. (eds) Lateralized Brain Functions. Neuromethods, vol 122. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6725-4_12
Download citation
DOI: https://doi.org/10.1007/978-1-4939-6725-4_12
Published:
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-6723-0
Online ISBN: 978-1-4939-6725-4
eBook Packages: Springer Protocols