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Oral Biology pp 127-138 | Cite as

The Oral Microbiota in Health and Disease: An Overview of Molecular Findings

  • José F. SiqueiraJr.Email author
  • Isabela N. Rôças
Part of the Methods in Molecular Biology book series (MIMB, volume 1537)

Abstract

Culture-independent nucleic acid technologies have been extensively applied to the analysis of oral bacterial communities associated with healthy and diseased conditions. These methods have confirmed and substantially expanded the findings from culture studies to reveal the oral microbial inhabitants and candidate pathogens associated with the major oral diseases. Over 1000 bacterial distinct species-level taxa have been identified in the oral cavity and studies using next-generation DNA sequencing approaches indicate that the breadth of bacterial diversity may be even much larger. Nucleic acid technologies have also been helpful in profiling bacterial communities and identifying disease-related patterns. This chapter provides an overview of the diversity and taxonomy of oral bacteria associated with health and disease.

Key words

Oral microbiology Molecular biology methods Taxonomy Oral diseases 

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© Springer Science+Business Media LLC 2017

Authors and Affiliations

  1. 1.Department ofEndodontics, Molecular Microbiology LaboratoryEstácio de Sá UniversityRio de JaneiroBrazil
  2. 2.Faculty of DentistryEstácio de Sá UniversityRio de JaneiroBrazil

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