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Practical Bioinformatics Analysis of MiRNA Data Using Online Tools

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Book cover MicroRNA Profiling

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1509))

Abstract

The purpose of this chapter is to provide a starting point for the analysis of miRNA array data, using freely available online suites of tools. This chapter does not describe how to perform analysis of primary array data, rather how to use the top differentially regulated miRNA (returned from comparing one miRNA group to another) as the starting point for further practical analysis.

Here we describe the methods and tools required to identify targets worthy of additional investigation, using the identified miRNA as a starting point. Importantly, this additional information (pathways targeted, gene expression, mRNA targets, miRNA families) can be used to positively inform any project.

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Author information

Authors and Affiliations

  1. Discipline of Surgery, College of Medicine, Lambe Institute for Translational Research, National University of Ireland, University Road, Galway, Ireland

    James A. L. Brown

  2. Discipline of Pathology, College of Medicine, Lambe Institute for Translational Research, National University of Ireland, Galway, Ireland

    Emer Bourke

Authors
  1. James A. L. Brown
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  2. Emer Bourke
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Corresponding author

Correspondence to James A. L. Brown .

Editor information

Editors and Affiliations

  1. Department of Science, Waterford Institute of Technology, Waterford, Ireland

    Sweta Rani

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© 2017 Springer Science+Business Media New York

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Brown, J.A.L., Bourke, E. (2017). Practical Bioinformatics Analysis of MiRNA Data Using Online Tools. In: Rani, S. (eds) MicroRNA Profiling. Methods in Molecular Biology, vol 1509. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6524-3_18

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  • DOI: https://doi.org/10.1007/978-1-4939-6524-3_18

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6522-9

  • Online ISBN: 978-1-4939-6524-3

  • eBook Packages: Springer Protocols

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