Abstract
Semaphorins, which were originally identified as axon-guidance molecules, also serve multiple functions in various phases of immune responses. In particular, several semaphorins regulate antigen presentation by dendritic cells (DCs) and resultant differentiation of CD4+ T cells. Here we describe a method for investigating both functions in vitro. This method might be used to obtain insight into novel aspects of semaphorin-mediated immunity.
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Nojima, S., Kumanogoh, A. (2017). Characterizing Semaphorin-Mediated Immune Responses Using an Antigen-Presentation Assay. In: Terman, J. (eds) Semaphorin Signaling. Methods in Molecular Biology, vol 1493. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6448-2_27
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DOI: https://doi.org/10.1007/978-1-4939-6448-2_27
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Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-6446-8
Online ISBN: 978-1-4939-6448-2
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