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Prediction of Protein Secondary Structure pp 137–158Cite as

How to Predict Disorder in a Protein of Interest

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1484))

Abstract

Currently available computational tools, which are many, provide a researcher with the multitude of options for prediction of intrinsic disorder in a protein of interest and for finding at least some of its disorder-based functions. This chapter provides a highly subjective guideline on how not to be lost in the “dark forest” of available tools for the analysis of intrinsic disorder. By no means it gives a unique pathway through this forest, but simply presents some of the tools the author uses in his everyday research.

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Acknowledgements

This work was supported in part by a grant from the Russian Science Foundation RSCF № 14-24-00131.

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Authors and Affiliations

  1. Department of Molecular Medicine and USF Health Byrd Alzheimer’s Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, 33612, USA

    Vladimir N. Uversky

  2. Institute for Biological Instrumentation, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russian Federation

    Vladimir N. Uversky

  3. Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federation

    Vladimir N. Uversky

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  1. Vladimir N. Uversky
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Correspondence to Vladimir N. Uversky .

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Editors and Affiliations

  1. Institute for Glycomics and School of Information and Communication Technology, Griffith University, Southport, Queensland, Australia

    Yaoqi Zhou

  2. Battelle Center for Mathematical Medicine, Nationwide Children’s Hospital, Columbus, Ohio, USA

    Andrzej Kloczkowski

  3. Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA

    Eshel Faraggi

  4. Institute for Glycomics and School of Information and Communication Technology, Griffith University, Southport, Queensland, Australia

    Yuedong Yang

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Uversky, V.N. (2017). How to Predict Disorder in a Protein of Interest. In: Zhou, Y., Kloczkowski, A., Faraggi, E., Yang, Y. (eds) Prediction of Protein Secondary Structure. Methods in Molecular Biology, vol 1484. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6406-2_11

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  • DOI: https://doi.org/10.1007/978-1-4939-6406-2_11

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6404-8

  • Online ISBN: 978-1-4939-6406-2

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