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Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools pp 201–216Cite as

Biogenesis and Functions of Exosomes and Extracellular Vesicles

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1448))

Abstract

Research on extracellular vesicles (EVs) is a new and emerging field that is rapidly growing. Many features of these structures still need to be described and discovered. This concerns their biogenesis, their release and cellular entrance mechanisms, as well as their functions, particularly in vivo. Hence our knowledge on EV is constantly evolving and sometimes changing. In our review we summarize the most important facts of our current knowledge about extracellular vesicles and described some of the assumed functions in the context of cancer and HIV infection.

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Authors and Affiliations

  1. Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander University of Erlangen-Nürnberg, Hartmannstr. 14, 91054, Erlangen, Germany

    Florian Dreyer & Andreas Baur

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  1. Florian Dreyer
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  2. Andreas Baur
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Correspondence to Andreas Baur .

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  1. Istituto Superiore di Sanità, National AIDS Center, Rome, Italy

    Maurizio Federico

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Dreyer, F., Baur, A. (2016). Biogenesis and Functions of Exosomes and Extracellular Vesicles. In: Federico, M. (eds) Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools. Methods in Molecular Biology, vol 1448. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3753-0_15

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  • DOI: https://doi.org/10.1007/978-1-4939-3753-0_15

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3751-6

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