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A Novel Collagen Dot Assay for Monitoring Cancer Cell Migration

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Breast Cancer

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1406))

Abstract

Cell migration is a critical determinant of cancer invasion and metastasis. Drugs targeting cancer cell migration have been hindered due to the lack of effective assays for monitoring cancer cell migration. Here we describe a novel method to microscopically monitor cell migration in a quantitative fashion. This assay can be used to study genes involved in cancer cell migration, as well as screening anticancer drugs that target this cellular process.

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Correspondence to Jian Cao .

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© 2016 Springer Science+Business Media New York

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Alford, V.M., Roth, E., Zhang, Q., Cao, J. (2016). A Novel Collagen Dot Assay for Monitoring Cancer Cell Migration. In: Cao, J. (eds) Breast Cancer. Methods in Molecular Biology, vol 1406. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3444-7_15

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  • DOI: https://doi.org/10.1007/978-1-4939-3444-7_15

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3442-3

  • Online ISBN: 978-1-4939-3444-7

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