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A Novel Collagen Dot Assay for Monitoring Cancer Cell Migration

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  • First Online:
Breast Cancer

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1406))

Abstract

Cell migration is a critical determinant of cancer invasion and metastasis. Drugs targeting cancer cell migration have been hindered due to the lack of effective assays for monitoring cancer cell migration. Here we describe a novel method to microscopically monitor cell migration in a quantitative fashion. This assay can be used to study genes involved in cancer cell migration, as well as screening anticancer drugs that target this cellular process.

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Author information

Authors and Affiliations

  1. Division of Cancer Prevention, Department of Medicine, Stony Brook University, 101 Nicolls Road, Stony Brook, NY, 11794, USA

    Vincent M. Alford, Eric Roth, Qian Zhang & Jian Cao

Authors
  1. Vincent M. Alford
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  2. Eric Roth
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  3. Qian Zhang
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  4. Jian Cao
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Corresponding author

Correspondence to Jian Cao .

Editor information

Editors and Affiliations

  1. School of Medicine, Stony Brook University, Stony Brook, New York, USA

    Jian Cao

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© 2016 Springer Science+Business Media New York

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Alford, V.M., Roth, E., Zhang, Q., Cao, J. (2016). A Novel Collagen Dot Assay for Monitoring Cancer Cell Migration. In: Cao, J. (eds) Breast Cancer. Methods in Molecular Biology, vol 1406. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3444-7_15

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  • DOI: https://doi.org/10.1007/978-1-4939-3444-7_15

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3442-3

  • Online ISBN: 978-1-4939-3444-7

  • eBook Packages: Springer Protocols

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