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Superantigens pp 133–147Cite as

Use of an Ex Vivo Porcine Mucosal Model to Study Superantigen Penetration

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1396))

Abstract

In vitro perfusion studies are frequently used to determine the penetration of compounds through skin and mucosa. Porcine tissue has been shown to be an excellent model for human tissue in terms of structure, function, and reactivity. We describe the use of porcine tissue ex-vivo in a continuous flow perfusion system to study the behavior of superantigens in this model.

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Author information

Authors and Affiliations

  1. Dows Institute for Dental Research, College of Dentistry, University of Iowa, Iowa City, IA, 52242, USA

    Christopher A. Squier & Mary J. Mantz

Authors
  1. Christopher A. Squier
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  2. Mary J. Mantz
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Corresponding author

Correspondence to Christopher A. Squier .

Editor information

Editors and Affiliations

  1. Science Department, Concordia University - Saint Paul, St. Paul, Minnesota, USA

    Amanda J. Brosnahan

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Squier, C.A., Mantz, M.J. (2016). Use of an Ex Vivo Porcine Mucosal Model to Study Superantigen Penetration. In: Brosnahan, A. (eds) Superantigens. Methods in Molecular Biology, vol 1396. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3344-0_12

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  • DOI: https://doi.org/10.1007/978-1-4939-3344-0_12

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3342-6

  • Online ISBN: 978-1-4939-3344-0

  • eBook Packages: Springer Protocols

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