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Cartilage Tissue Engineering pp 203–219Cite as

Mechanobioreactors for Cartilage Tissue Engineering

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1340))

Abstract

Mechanical stimulation is an effective method to increase extracellular matrix synthesis and to improve the mechanical properties of tissue-engineered cartilage constructs. In this chapter, we describe valuable methods of imposing direct mechanical stimuli (compression or shear) to tissue-engineered cartilage constructs as well as some common analytical methods used to quantify the effects of mechanical stimuli after short-term or long-term loading.

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References

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Author information

Authors and Affiliations

  1. Department of Mechanical & Materials Engineering, Queen’s University, Kingston, Canada

    Joanna F. Weber M.A.Sc. & Stephen D. Waldman Ph.D., P.Eng.

  2. Human Mobility Research Centre, Kingston General Hospital and Queen’s University, Kingston, Canada

    Joanna F. Weber M.A.Sc.

  3. Kennan Research Centre, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, 30 Bond Street, Toronto, Canada, M5B 1W8

    Joanna F. Weber M.A.Sc., Roman Perez Ph.D. & Stephen D. Waldman Ph.D., P.Eng.

  4. Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea

    Roman Perez Ph.D.

  5. Department of Chemical Engineering, Ryerson University, Kerr Hall South (KHS 241), 50 Gould Street, Toronto, ON, Canada, M5B 2K3

    Stephen D. Waldman Ph.D., P.Eng.

Authors
  1. Joanna F. Weber M.A.Sc.
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  2. Roman Perez Ph.D.
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  3. Stephen D. Waldman Ph.D., P.Eng.
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Corresponding author

Correspondence to Stephen D. Waldman Ph.D., P.Eng. .

Editor information

Editors and Affiliations

  1. Swinburne University of Technology, Faculty of Science, Engineering and Technology, Hawthorn, Melbourne, Victoria, Australia

    Pauline M. Doran

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Weber, J.F., Perez, R., Waldman, S.D. (2015). Mechanobioreactors for Cartilage Tissue Engineering. In: Doran, P. (eds) Cartilage Tissue Engineering. Methods in Molecular Biology, vol 1340. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2938-2_15

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  • DOI: https://doi.org/10.1007/978-1-4939-2938-2_15

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-2937-5

  • Online ISBN: 978-1-4939-2938-2

  • eBook Packages: Springer Protocols

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