Abstract
In the late 1960s and early 1970s, characterization of arginylation has been spearheaded via biochemical studies that enabled the first characterization of ATE1 and its substrate specificity. This essay summarized the recollections and insights from the era of research that followed from the original discovery of arginylation and led up to the identification of the arginylation enzyme.
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References
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Acknowledgments
I was fortunate to have very able students and fellows who shared my interest in aminoacyl transferases. They were, in alphabetical order, Charles E. Deutch, Hiroo Horinishi, Michael J. Leibowitz, Margaret Savage, and Richard C. Scarpulla.
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Soffer, R.L. (2015). Arginyltransferase: A Personal and Historical Perspective. In: Kashina, A. (eds) Protein Arginylation. Methods in Molecular Biology, vol 1337. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2935-1_3
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DOI: https://doi.org/10.1007/978-1-4939-2935-1_3
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-2934-4
Online ISBN: 978-1-4939-2935-1
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