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VEGF Signaling pp 91–120Cite as

An Overview of VEGF-Mediated Signal Transduction

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1332))

Abstract

Vascular endothelial growth factor (VEGF) plays a fundamental role in angiogenesis and endothelial cell biology, and has been the subject of intense study as a result. VEGF acts via a diverse and complex range of signaling pathways, with new targets constantly being discovered. This review attempts to summarize the current state of knowledge regarding VEGF cell signaling in endothelial and cardiovascular biology, with a particular emphasis on its role in angiogenesis.

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Acknowledgment

Supported by BHF Programme Grant RG/06/003.

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Authors and Affiliations

  1. Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, Rayne Building, 5 University Street, London, WC1E 6JF, UK

    Ian Evans

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  1. Ian Evans
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Correspondence to Ian Evans .

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  1. Caversham, Reading, United Kingdom

    Lorna Fiedler

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Evans, I. (2015). An Overview of VEGF-Mediated Signal Transduction. In: Fiedler, L. (eds) VEGF Signaling. Methods in Molecular Biology, vol 1332. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2917-7_7

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  • DOI: https://doi.org/10.1007/978-1-4939-2917-7_7

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-2916-0

  • Online ISBN: 978-1-4939-2917-7

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