Abstract
Phlorotannins are a class of polyphenols found in brown seaweeds that have significant potential for use as therapeutics, owing to their wide range of bioactivities. Molecular characterization of phlorotannin-enriched extracts is challenging due to the extreme sample complexity and the wide range of molecular weights observed. Herein, we describe a method for characterizing phlorotannins employing ultrahigh-pressure liquid chromatography (UHPLC) operating in hydrophilic interaction liquid chromatography (HILIC) mode combined with high-resolution mass spectrometry (HRMS).
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Melanson, J.E., MacKinnon, S.L. (2015). Characterization of Phlorotannins from Brown Algae by LC-HRMS. In: Stengel, D., Connan, S. (eds) Natural Products From Marine Algae. Methods in Molecular Biology, vol 1308. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2684-8_16
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DOI: https://doi.org/10.1007/978-1-4939-2684-8_16
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-2683-1
Online ISBN: 978-1-4939-2684-8
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