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The Emerging Role of Metalloproteomics in Alzheimer’s Disease Research

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Systems Biology of Alzheimer's Disease

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1303))

Abstract

Metals are increasingly recognized to have an important role in molecular processes underlying Alzheimer’s disease (AD). This chapter discusses the current role of metals in AD and expands on the development of metalloproteomics and how the recent advances in analytical technology will allow detailed investigation of metalloproteins. Investigation of individual metalloproteins will yield new mechanistic details about the role of metals in AD.

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Author information

Authors and Affiliations

  1. The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia

    Dominic J. Hare, Alan Rembach & Blaine R. Roberts

  2. Elemental Bio-Imaging Facility, University of Technology Sydney, Broadway, NSW, Australia

    Dominic J. Hare

Authors
  1. Dominic J. Hare
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  2. Alan Rembach
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  3. Blaine R. Roberts
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Correspondence to Blaine R. Roberts .

Editor information

Editors and Affiliations

  1. Department of Biochemistry & Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom

    Juan I. Castrillo

  2. Department of Biochemistry & Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom

    Stephen G. Oliver

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Hare, D.J., Rembach, A., Roberts, B.R. (2016). The Emerging Role of Metalloproteomics in Alzheimer’s Disease Research. In: Castrillo, J., Oliver, S. (eds) Systems Biology of Alzheimer's Disease. Methods in Molecular Biology, vol 1303. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2627-5_22

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  • DOI: https://doi.org/10.1007/978-1-4939-2627-5_22

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-2626-8

  • Online ISBN: 978-1-4939-2627-5

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