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Stress and Spatial Maze Performance in the Rat

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The Maze Book

Part of the book series: Neuromethods ((NM,volume 94))

Abstract

Stress is frequently used to describe an undesirable psychological or physical state, and often evokes thoughts of frustration, worry, or anxiety. Despite its predominantly negative connotation, stress is necessary for an organism to successfully adapt to the environment. One of the major challenges for an organism is to find a balance between brief and adaptive stress while avoiding prolonged or excessive stress, which can be detrimental to both physiological and cognitive function. This chapter provides a historical perspective and broad overview of the stress response and describes the numerous types of stressors and paradigms used in animal research, with a focus on the effects of these stressors on spatial maze learning and memory. In addition, practical details on how to deal with the nuances of stressors and stress responses in behavioral testing are discussed.

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Acknowledgements

The authors would like to thank Pooja R. Paode for her assistance with the photography in Fig. 3.

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Authors and Affiliations

  1. Department of Psychology, Hendrix College, 1600 Washington Ave., Conway, Arkansas, 72032, USA

    Sara B. Taylor

  2. Behavioral Neuroscience Program, Department of Psychology, Arizona State University, 1104, 950 S. McAllister Ave., Tempe, AZ, 85287, USA

    Cheryl D. Conrad Ph.D. & M. Foster Olive

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  1. Sara B. Taylor
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  2. Cheryl D. Conrad Ph.D.
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  3. M. Foster Olive
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Correspondence to Cheryl D. Conrad Ph.D. .

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  1. Arizona State University, Tempe, Arizona, USA

    Heather A. Bimonte-Nelson

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Taylor, S.B., Conrad, C.D., Olive, M.F. (2015). Stress and Spatial Maze Performance in the Rat. In: Bimonte-Nelson, H. (eds) The Maze Book. Neuromethods, vol 94. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2159-1_8

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