Sepsis pp 17-33 | Cite as

Clinical Aspects of Sepsis: An Overview

  • Giacomo Monti
  • Giovanni LandoniEmail author
  • Daiana Taddeo
  • Francesca Isella
  • Alberto Zangrillo
Part of the Methods in Molecular Biology book series (MIMB, volume 1237)


Sepsis is one of the oldest and most elusive syndromes in medicine. With the confirmation of germ theory by Semmelweis, Pasteur, and others, sepsis was considered as a systemic infection by a pathogenic organism. Although the germ is probably the beginning of the syndrome and one of the major enemies to be identified and fought, sepsis is something wider and more elusive. In this chapter clinically relevant themes of sepsis will be approached to provide an insight of everyday clinical practice for healthcare workers often not directly involved in the patient’s management.

Key words

Sepsis Severe sepsis Septic shock Sites of infection 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Giacomo Monti
    • 1
  • Giovanni Landoni
    • 2
    Email author
  • Daiana Taddeo
    • 1
  • Francesca Isella
    • 1
  • Alberto Zangrillo
    • 2
  1. 1.Department of Anesthesia and Intensive CareIRCCS San Raffaele Scientific InstituteMilanItaly
  2. 2.Department of Anesthesia and Intensive CareIRCCS San Raffaele Scientific Insitute and University Vita-Salute San RaffaeleMilanItaly

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