Eosinophils pp 251-255 | Cite as

Eosinophil Interactions: Antigen Presentation

  • Praveen AkuthotaEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1178)


Eosinophils have been demonstrated in a variety of experimental models to express MHC Class II and co-stimulatory molecules necessary to act as antigen presenting cells (APCs). They also have been experimentally observed to use these expressed proteins to function as APCs. This chapter reviews basic techniques to allow for in vitro and ex vivo experimentation of human and murine eosinophil APC function.

Key words

Eosinophils Antigen presentation Class II major histocompatibility antigens Granulocytes Humans 



This work was supported by a HOPE Pilot Grant from the American Partnership for Eosinophilic Disorders to P.A.


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Copyright information

© Springer Science+Business Media, New York 2014

Authors and Affiliations

  1. 1.Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonUSA
  2. 2.Division of Allergy and Inflammation, Department of Medicine, Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonUSA

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