Eosinophil Interactions: Antigen Presentation
Eosinophils have been demonstrated in a variety of experimental models to express MHC Class II and co-stimulatory molecules necessary to act as antigen presenting cells (APCs). They also have been experimentally observed to use these expressed proteins to function as APCs. This chapter reviews basic techniques to allow for in vitro and ex vivo experimentation of human and murine eosinophil APC function.
Key wordsEosinophils Antigen presentation Class II major histocompatibility antigens Granulocytes Humans
This work was supported by a HOPE Pilot Grant from the American Partnership for Eosinophilic Disorders to P.A.