Abstract
Protein-coding sequences are characterized by a period-3 free energy signal that arises from the interaction between the 3′-terminal nucleotides of the 18S rRNA and the mRNA. Such a signal is not present in noncoding sequences such as introns and intergenic regions and can be used for pseudogene identification.
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Xing, C. (2014). Methods of Identification of Pseudogenes Based on Functionality: Hybridization of 18S rRNA and mRNA During Translation. In: Poliseno, L. (eds) Pseudogenes. Methods in Molecular Biology, vol 1167. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-0835-6_5
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DOI: https://doi.org/10.1007/978-1-4939-0835-6_5
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