Abstract
Magnetic resonance imaging can be utilized as a quantitative and noninvasive method to image cerebral blood flow. The two most common techniques used to detect cerebral blood flow are dynamic susceptibility contrast (DSC) perfusion MRI and arterial spin labeling perfusion MRI. Herein we describe the use of these two techniques to measure cerebral blood flow in rodents, including methods, analysis, and important considerations when utilizing these techniques.
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Acknowledgements
This work is supported in part by the National Institute of Neurological Disorders and Stroke, the National Institute of Health (R01 NS045879), and the Established Investigator Award (EIA 0940104N) from the American Heart Association.
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Muir, E.R., Watts, L.T., Tiwari, Y.V., Bresnen, A., Shen, Q., Duong, T.Q. (2014). Quantitative Cerebral Blood Flow Measurements Using MRI. In: Milner, R. (eds) Cerebral Angiogenesis. Methods in Molecular Biology, vol 1135. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-0320-7_17
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DOI: https://doi.org/10.1007/978-1-4939-0320-7_17
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-0319-1
Online ISBN: 978-1-4939-0320-7
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