Gene Electrotransfer in Clinical Trials

  • Julie Gehl
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1121)

Abstract

Electroporation is increasingly being used for delivery of chemotherapy to tumors. Likewise, gene delivery by electroporation is rapidly gaining momentum for both vaccination purposes and for delivery of genes coding for other therapeutic molecules, such as chronic diseases or cancer. This chapter describes how gene therapy may be performed using electric pulses to enhance uptake and expression.

Key words

Gene therapy Gene delivery Electrotransfer Electroporation Anesthesia Standard operating procedures 

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Julie Gehl
    • 1
  1. 1.Department of Oncology, Center for Experimental Drug and Gene ElectrotransferCopenhagen University HospitalHerlevDenmark

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