Abstract
Avian infection studies with influenza A are an important means of assessing host susceptibility, viral pathogenesis, host responses to infection, mechanisms of transmission, viral pathotype, and viral evolution. Complex systems and natural settings may also be explored with carefully designed infection studies. In this chapter, we explore the elements of infection studies, general guidelines for choosing a virus to use, host selection, and many aspects of study design.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Hall JS, Franson JC, Gill RE, Meteyer CU, TeSlaa JL, Nashold S, Dusek RJ, Ip HS (2011) Experimental challenge and pathology of highly pathogenic avian influenza virus H5N1 in dunlin (Calidris alpina), an intercontinental migrant shorebird species. Influenza Other Respir Viruses 5(5):365–372. https://doi.org/10.1111/j.1750-2659.2011.00238.x
Yee KS, Cardona CJ, Carpenter TE (2009) Transmission of low-pathogenicity avian influenza virus of subtype H6N2 from chickens to Pekin ducks and Japanese quail (Coturnix coturnix japonica). Avian Pathol 38(1):59–64. https://doi.org/10.1080/03079450802632023
Yee KS, Carpenter TE, Farver TB, Cardona CJ (2009) An evaluation of transmission routes for low pathogenicity avian influenza virus among chickens sold in live bird markets. Virology 394(1):19–27. https://doi.org/10.1016/j.virol.2009.08.017
Swayne DE (1997) Pathobiology of H5N2 Mexican avian influenza virus infections of chickens. Vet Pathol 34(6):557–567. https://doi.org/10.1177/030098589703400603
Spackman E, Gelb J Jr, Preskenis LA, Ladman BS, Pope CR, Pantin-Jackwood MJ, McKinley ET (2010) The pathogenesis of low pathogenicity H7 avian influenza viruses in chickens, ducks and turkeys. Virol J 7:331. https://doi.org/10.1186/1743-422X-7-331
Wasilenko JL, Arafa AM, Selim AA, Hassan MK, Aly MM, Ali A, Nassif S, Elebiary E, Balish A, Klimov A, Suarez DL, Swayne DE, Pantin-Jackwood MJ (2011) Pathogenicity of two Egyptian H5N1 highly pathogenic avian influenza viruses in domestic ducks. Arch Virol 156(1):37–51. https://doi.org/10.1007/s00705-010-0813-y
Swayne DE, Pantin-Jackwood M, Kapczynski D, Spackman E, Suarez DL (2009) Susceptibility of poultry to pandemic (H1N1) 2009 virus. Emerg Infect Dis 15(12):2061–2063
Perkins LE, Swayne DE (2001) Pathobiology of a/chicken/Hong Kong/220/97 (H5N1) avian influenza virus in seven gallinaceous species. Vet Pathol 38(2):149–164
Perkins LE, Swayne DE (2003) Comparative susceptibility of selected avian and mammalian species to a Hong Kong-origin H5N1 high-pathogenicity avian influenza virus. Avian Dis 47(3 Suppl):956–967
Faust C, Stallknecht D, Swayne D, Brown J (2009) Filter-feeding bivalves can remove avian influenza viruses from water and reduce infectivity. Proc Biol Sci 276(1673):3727–3735. https://doi.org/10.1098/rspb.2009.0572
Brown JD, Stallknecht DE, Swayne DE (2008) Experimental infections of herring gulls (Larus argentatus) with H5N1 highly pathogenic avian influenza viruses by intranasal inoculation of virus and ingestion of virus-infected chicken meat. Avian Pathol 37(4):393–397. https://doi.org/10.1080/03079450802216595
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.
About this protocol
Cite this protocol
Cardona, C.J., Halvorson, D.A., Hall, J., Pantin-Jackwood, M.J., Brown, J.D. (2020). Conducting Influenza Virus Pathogenesis Studies in Avian Species. In: Spackman, E. (eds) Animal Influenza Virus. Methods in Molecular Biology, vol 2123. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0346-8_15
Download citation
DOI: https://doi.org/10.1007/978-1-0716-0346-8_15
Published:
Publisher Name: Humana, New York, NY
Print ISBN: 978-1-0716-0345-1
Online ISBN: 978-1-0716-0346-8
eBook Packages: Springer Protocols